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Fasting Status and Circadian Variation Must be Considered When Performing AUC‐based Therapeutic Drug Monitoring of Tacrolimus in Renal Transplant Recipients

Therapeutic drug monitoring (TDM) is mandatory for the immunosuppressive drug tacrolimus (Tac). For clinical applicability, TDM is performed using morning trough concentrations. With recent developments making tacrolimus concentration determination possible in capillary microsamples and Bayesian est...

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Detalles Bibliográficos
Autores principales: Gustavsen, Marte Theie, Midtvedt, Karsten, Robertsen, Ida, Woillard, Jean‐Baptiste, Debord, Jean, Klaasen, Rolf Anton, Vethe, Nils Tore, Bergan, Stein, Åsberg, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719361/
https://www.ncbi.nlm.nih.gov/pubmed/32652886
http://dx.doi.org/10.1111/cts.12833