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Dose‐Dependent Acute Effects of Everolimus Administration on Immunological, Neuroendocrine and Psychological Parameters in Healthy Men

The rapamycin analogue everolimus (EVR) is a potent inhibitor of the mammalian target of rapamycin (mTOR) and clinically used to prevent allograft rejections as well as tumor growth. The pharmacokinetic and immunosuppressive efficacy of EVR have been extensively reported in patient populations and i...

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Detalles Bibliográficos
Autores principales: Hörbelt, Tina, Kahl, Anna Lena, Kolbe, Frederike, Hetze, Susann, Wilde, Benjamin, Witzke, Oliver, Schedlowski, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719391/
https://www.ncbi.nlm.nih.gov/pubmed/32475067
http://dx.doi.org/10.1111/cts.12812