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CYP2C19 Allele Frequencies in Over 2.2 Million Direct‐to‐Consumer Genetics Research Participants and the Potential Implication for Prescriptions in a Large Health System

Understanding the prevalence of clinically relevant pharmacogenetic variants using large unselected populations is critical for gauging the potential clinical impact of widespread preemptive pharmacogenetic testing. To this end, we assessed the frequencies and ethnic distribution of the three most c...

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Detalles Bibliográficos
Autores principales: Ionova, Yelena, Ashenhurst, James, Zhan, Jianan, Nhan, Hoang, Kosinski, Cindy, Tamraz, Bani, Chubb, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719394/
https://www.ncbi.nlm.nih.gov/pubmed/32506666
http://dx.doi.org/10.1111/cts.12830