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A Novel Cryptococcal Meningitis Therapy: The Combination of Amphotericin B and Posaconazole Promotes the Distribution of Amphotericin B in the Brain Tissue

The deficient brain tissue distribution of amphotericin B (AMPB) seriously restricts its treatment for the clinical efficacy of cryptococcus neoformans meningitis (CNM). We strive to develop a tactic to increase its concentration in brain tissue. We aimed to investigate whether the combination of AM...

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Detalles Bibliográficos
Autores principales: Yang, Ming, Cheng, Lin, Dai, Qing, Yang, Bo, Yuan, Qian, Yu, MingJie, Feng, Wei, Sun, Fengjun, Xia, Peiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719495/
https://www.ncbi.nlm.nih.gov/pubmed/33313322
http://dx.doi.org/10.1155/2020/8878158