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A Novel Cryptococcal Meningitis Therapy: The Combination of Amphotericin B and Posaconazole Promotes the Distribution of Amphotericin B in the Brain Tissue
The deficient brain tissue distribution of amphotericin B (AMPB) seriously restricts its treatment for the clinical efficacy of cryptococcus neoformans meningitis (CNM). We strive to develop a tactic to increase its concentration in brain tissue. We aimed to investigate whether the combination of AM...
Autores principales: | Yang, Ming, Cheng, Lin, Dai, Qing, Yang, Bo, Yuan, Qian, Yu, MingJie, Feng, Wei, Sun, Fengjun, Xia, Peiyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719495/ https://www.ncbi.nlm.nih.gov/pubmed/33313322 http://dx.doi.org/10.1155/2020/8878158 |
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