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Increased Frequencies of Switched Memory B Cells and Plasmablasts in Peripheral Blood from Patients with ANCA-Associated Vasculitis

B cells are thought to play a central role in the pathogenesis of antineutrophil cytoplasmic antibody- (ANCA-) associated vasculitis (AAV). ANCAs have been proposed to cause vasculitis by activating primed neutrophils to damage small blood vessels. We studied a cohort of AAV patients of which a majo...

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Detalles Bibliográficos
Autores principales: Elmér, Evelina, Smargianaki, Sofia, Pettersson, Åsa, Skattum, Lillemor, Ohlsson, Sophie, Hellmark, Thomas, Johansson, Åsa C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719539/
https://www.ncbi.nlm.nih.gov/pubmed/33313327
http://dx.doi.org/10.1155/2020/8209737