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Terminal Respiratory Oxidases: A Targetables Vulnerability of Mycobacterial Bioenergetics?

Recently, ATP synthase inhibitor Bedaquiline was approved for the treatment of multi-drug resistant tuberculosis emphasizing the importance of oxidative phosphorylation for the survival of mycobacteria. ATP synthesis is primarily dependent on the generation of proton motive force through the electro...

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Detalles Bibliográficos
Autores principales: Bajeli, Sapna, Baid, Navin, Kaur, Manjot, Pawar, Ganesh P., Chaudhari, Vinod D., Kumar, Ashwani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719681/
https://www.ncbi.nlm.nih.gov/pubmed/33330134
http://dx.doi.org/10.3389/fcimb.2020.589318