Cargando…
Terminal Respiratory Oxidases: A Targetables Vulnerability of Mycobacterial Bioenergetics?
Recently, ATP synthase inhibitor Bedaquiline was approved for the treatment of multi-drug resistant tuberculosis emphasizing the importance of oxidative phosphorylation for the survival of mycobacteria. ATP synthesis is primarily dependent on the generation of proton motive force through the electro...
Autores principales: | Bajeli, Sapna, Baid, Navin, Kaur, Manjot, Pawar, Ganesh P., Chaudhari, Vinod D., Kumar, Ashwani |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719681/ https://www.ncbi.nlm.nih.gov/pubmed/33330134 http://dx.doi.org/10.3389/fcimb.2020.589318 |
Ejemplares similares
-
Bioenergetics of Mycobacterium: An Emerging Landscape for Drug Discovery
por: Iqbal, Iram Khan, et al.
Publicado: (2018) -
Mycobacterial Control of Host Mitochondria: Bioenergetic and Metabolic Changes Shaping Cell Fate and Infection Outcome
por: Mohareer, Krishnaveni, et al.
Publicado: (2020) -
Uncovering interactions between mycobacterial respiratory complexes to target drug-resistant Mycobacterium tuberculosis
por: McNeil, Matthew B., et al.
Publicado: (2022) -
Bioenergetic Inhibitors: Antibiotic Efficacy and Mechanisms of Action in Mycobacterium tuberculosis
por: Hasenoehrl, Erik J., et al.
Publicado: (2021) -
Understanding and Exploiting the Effect of Tuberculosis Antimicrobials on Host Mitochondrial Function and Bioenergetics
por: Cahill, Christina, et al.
Publicado: (2020)