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The HLTF–PARP1 interaction in the progression and stability of damaged replication forks caused by methyl methanesulfonate

Human HLTF participates in the lesion-bypass mechanism through the fork reversal structure, known as template switching of post-replication repair. However, the mechanism by which HLTF promotes the replication progression and fork stability of damaged forks remains unclear. Here, we identify a novel...

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Detalles Bibliográficos
Autores principales: Shiu, Jia-Lin, Wu, Cheng-Kuei, Chang, Song-Bin, Sun, Yan-Jhih, Chen, Yen-Ju, Lai, Chien-Chen, Chiu, Wen-Tai, Chang, Wen-Tsan, Myung, Kyungjae, Su, Wen-Pin, Liaw, Hungjiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719709/
https://www.ncbi.nlm.nih.gov/pubmed/33281189
http://dx.doi.org/10.1038/s41389-020-00289-5