Methadone Suppresses Neuronal Function and Maturation in Human Cortical Organoids

Accumulating evidence has suggested that prenatal exposure to methadone causes multiple adverse effects on human brain development. Methadone not only suppresses fetal neurobehavior and alters neural maturation, but also leads to long-term neurological impairment. Due to logistical and ethical issue...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Yao, Hang, Dwivedi, Ila, Negraes, Priscilla D., Zhao, Helen W., Wang, Juan, Trujillo, Cleber A., Muotri, Alysson R., Haddad, Gabriel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719724/
https://www.ncbi.nlm.nih.gov/pubmed/33328864
http://dx.doi.org/10.3389/fnins.2020.593248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719724/
https://www.ncbi.nlm.nih.gov/pubmed/33328864
http://dx.doi.org/10.3389/fnins.2020.593248

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