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Methadone Suppresses Neuronal Function and Maturation in Human Cortical Organoids
Accumulating evidence has suggested that prenatal exposure to methadone causes multiple adverse effects on human brain development. Methadone not only suppresses fetal neurobehavior and alters neural maturation, but also leads to long-term neurological impairment. Due to logistical and ethical issue...
Autores principales: | Wu, Wei, Yao, Hang, Dwivedi, Ila, Negraes, Priscilla D., Zhao, Helen W., Wang, Juan, Trujillo, Cleber A., Muotri, Alysson R., Haddad, Gabriel G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719724/ https://www.ncbi.nlm.nih.gov/pubmed/33328864 http://dx.doi.org/10.3389/fnins.2020.593248 |
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