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Sleep Deprivation Aggravates Cognitive Impairment by the Alteration of Hippocampal Neuronal Activity and the Density of Dendritic Spine in Isoflurane-Exposed Mice

Isoflurane contributes to cognitive deficits when used as a general anesthetic, and so does sleep deprivation (SD). Patients usually suffer from insomnia before an operation due to anxiety, fear, and other factors. It remains unclear whether preoperative SD exacerbates cognitive impairment induced b...

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Detalles Bibliográficos
Autores principales: Zhang, Kai, Lian, Naqi, Ding, Ran, Guo, Cunle, Dong, Xi, Li, Yuanyuan, Wei, Sheng, Jiao, Qingyan, Yu, Yonghao, Shen, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719754/
https://www.ncbi.nlm.nih.gov/pubmed/33328920
http://dx.doi.org/10.3389/fnbeh.2020.589176