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Sleep Deprivation Aggravates Cognitive Impairment by the Alteration of Hippocampal Neuronal Activity and the Density of Dendritic Spine in Isoflurane-Exposed Mice
Isoflurane contributes to cognitive deficits when used as a general anesthetic, and so does sleep deprivation (SD). Patients usually suffer from insomnia before an operation due to anxiety, fear, and other factors. It remains unclear whether preoperative SD exacerbates cognitive impairment induced b...
Autores principales: | Zhang, Kai, Lian, Naqi, Ding, Ran, Guo, Cunle, Dong, Xi, Li, Yuanyuan, Wei, Sheng, Jiao, Qingyan, Yu, Yonghao, Shen, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719754/ https://www.ncbi.nlm.nih.gov/pubmed/33328920 http://dx.doi.org/10.3389/fnbeh.2020.589176 |
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