The Combination of CD8αα and Peptide-MHC-I in a Face-to-Face Mode Promotes Chicken γδT Cells Response

The CD8αα homodimer is crucial to both thymic T cell selection and the antigen recognition of cytotoxic T cells. The CD8-pMHC-I interaction can enhance CTL immunity via stabilizing the TCR-pMHC-I interaction and optimizing the cross-reactivity and Ag sensitivity of CD8(+) T cells at various stages o...

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Detalles Bibliográficos
Autores principales: Liu, Yanjie, Chen, Rong, Liang, Ruiying, Sun, Beibei, Wu, Yanan, Zhang, Lijie, Kaufman, Jim, Xia, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719794/
https://www.ncbi.nlm.nih.gov/pubmed/33329601
http://dx.doi.org/10.3389/fimmu.2020.605085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719794/
https://www.ncbi.nlm.nih.gov/pubmed/33329601
http://dx.doi.org/10.3389/fimmu.2020.605085

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