Get rid of pancreatic cancer by inhibiting garbage disposal?: Comment on “UAE1 Inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer” by Rehemtulla et al

• stress pathways including the ER stress, the proteasome and the unfolded protein response (UPR) are increasingly reported to be suitable targets in PDAC; • UAE1 is the most abundant of two ubiquitin activating enzymes (UAE) regulating the initial step of the ER stress associated protein degradatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Geismann, Claudia, Arlt, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Preview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720072/
https://www.ncbi.nlm.nih.gov/pubmed/33285366
http://dx.doi.org/10.1016/j.tranon.2020.100968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720072/
https://www.ncbi.nlm.nih.gov/pubmed/33285366
http://dx.doi.org/10.1016/j.tranon.2020.100968

Ejemplares similares