Cargando…
Get rid of pancreatic cancer by inhibiting garbage disposal?: Comment on “UAE1 Inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer” by Rehemtulla et al
• stress pathways including the ER stress, the proteasome and the unfolded protein response (UPR) are increasingly reported to be suitable targets in PDAC; • UAE1 is the most abundant of two ubiquitin activating enzymes (UAE) regulating the initial step of the ER stress associated protein degradatio...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Neoplasia Press
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720072/ https://www.ncbi.nlm.nih.gov/pubmed/33285366 http://dx.doi.org/10.1016/j.tranon.2020.100968 |