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A hydrogel-based in vitro assay for the fast prediction of antibiotic accumulation in Gram-negative bacteria

The pipeline of antibiotics has been for decades on an alarmingly low level. Considering the steadily emerging antibiotic resistance, novel tools are needed for early and easy identification of effective anti-infective compounds. In Gram-negative bacteria, the uptake of anti-infectives is especially...

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Detalles Bibliográficos
Autores principales: Richter, Robert, Kamal, Mohamed.A.M., García-Rivera, Mariel A., Kaspar, Jerome, Junk, Maximilian, Elgaher, Walid A.M., Srikakulam, Sanjay Kumar, Gress, Alexander, Beckmann, Anja, Grißmer, Alexander, Meier, Carola, Vielhaber, Michael, Kalinina, Olga, Hirsch, Anna K.H., Hartmann, Rolf W., Brönstrup, Mark, Schneider-Daum, Nicole, Lehr, Claus-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720078/
https://www.ncbi.nlm.nih.gov/pubmed/33313504
http://dx.doi.org/10.1016/j.mtbio.2020.100084