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A hydrogel-based in vitro assay for the fast prediction of antibiotic accumulation in Gram-negative bacteria
The pipeline of antibiotics has been for decades on an alarmingly low level. Considering the steadily emerging antibiotic resistance, novel tools are needed for early and easy identification of effective anti-infective compounds. In Gram-negative bacteria, the uptake of anti-infectives is especially...
Autores principales: | Richter, Robert, Kamal, Mohamed.A.M., García-Rivera, Mariel A., Kaspar, Jerome, Junk, Maximilian, Elgaher, Walid A.M., Srikakulam, Sanjay Kumar, Gress, Alexander, Beckmann, Anja, Grißmer, Alexander, Meier, Carola, Vielhaber, Michael, Kalinina, Olga, Hirsch, Anna K.H., Hartmann, Rolf W., Brönstrup, Mark, Schneider-Daum, Nicole, Lehr, Claus-Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720078/ https://www.ncbi.nlm.nih.gov/pubmed/33313504 http://dx.doi.org/10.1016/j.mtbio.2020.100084 |
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