Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin

Polycomb repressive complex 2 (PRC2) installs and spreads repressive histone methylation marks on eukaryotic chromosomes. Because of the key roles that PRC2 plays in development and disease, how this epigenetic machinery interacts with DNA and nucleosomes is of major interest. Nonetheless, the mecha...

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Detalles Bibliográficos
Autores principales: Leicher, Rachel, Ge, Eva J., Lin, Xingcheng, Reynolds, Matthew J., Xie, Wenjun, Walz, Thomas, Zhang, Bin, Muir, Tom W., Liu, Shixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720148/
https://www.ncbi.nlm.nih.gov/pubmed/33208532
http://dx.doi.org/10.1073/pnas.2003395117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720148/
https://www.ncbi.nlm.nih.gov/pubmed/33208532
http://dx.doi.org/10.1073/pnas.2003395117

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