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Structure of eukaryotic DNA polymerase δ bound to the PCNA clamp while encircling DNA

The DNA polymerase (Pol) δ of Saccharomyces cerevisiae (S.c.) is composed of the catalytic subunit Pol3 along with two regulatory subunits, Pol31 and Pol32. Pol δ binds to proliferating cell nuclear antigen (PCNA) and functions in genome replication, repair, and recombination. Unique among DNA polym...

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Detalles Bibliográficos
Autores principales: Zheng, Fengwei, Georgescu, Roxana E., Li, Huilin, O’Donnell, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720213/
https://www.ncbi.nlm.nih.gov/pubmed/33203675
http://dx.doi.org/10.1073/pnas.2017637117