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Structure of eukaryotic DNA polymerase δ bound to the PCNA clamp while encircling DNA
The DNA polymerase (Pol) δ of Saccharomyces cerevisiae (S.c.) is composed of the catalytic subunit Pol3 along with two regulatory subunits, Pol31 and Pol32. Pol δ binds to proliferating cell nuclear antigen (PCNA) and functions in genome replication, repair, and recombination. Unique among DNA polym...
Autores principales: | Zheng, Fengwei, Georgescu, Roxana E., Li, Huilin, O’Donnell, Michael E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720213/ https://www.ncbi.nlm.nih.gov/pubmed/33203675 http://dx.doi.org/10.1073/pnas.2017637117 |
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