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Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer’s disease

Neuronal dendritic and synaptic pruning are early features of neurodegenerative diseases, including Alzheimer’s disease. In addition to brain pathology, amyloid plaque deposition, microglial activation, and cell loss occur in the retinas of human patients and animal models of Alzheimer’s disease. Re...

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Detalles Bibliográficos
Autores principales: Bevan, Ryan J., Hughes, Tim R., Williams, Pete A., Good, Mark A., Morgan, B. Paul, Morgan, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720390/
https://www.ncbi.nlm.nih.gov/pubmed/33287900
http://dx.doi.org/10.1186/s40478-020-01094-2