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O(6)-methylguanine DNA methyltransferase and glucose transporter 2 in foregut and hindgut gastrointestinal neuroendocrine neoplasms

BACKGROUND: Streptozocin (STZ) is used for treating both pancreatic (PanNET) and gastrointestinal (GI-NET) neuroendocrine tumors but its therapeutic efficacy is relatively low in GI-NETs. Therefore, it has become pivotal to select GI-NET patients who could benefit from STZ treatment. STZ is transpor...

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Detalles Bibliográficos
Autores principales: Watanabe, Hirofumi, Yamazaki, Yuto, Fujishima, Fumiyoshi, Izumi, Komoto, Imamura, Masayuki, Hijioka, Susumu, Toriyama, Kazuhiro, Yatabe, Yasushi, Kudo, Atsushi, Motoi, Fuyuhiko, Unno, Michiaki, Sasano, Hironobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720403/
https://www.ncbi.nlm.nih.gov/pubmed/33287738
http://dx.doi.org/10.1186/s12885-020-07579-6