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Overlapping-sample Mendelian randomisation with multiple exposures: a Bayesian approach
BACKGROUND: Mendelian randomization (MR) has been widely applied to causal inference in medical research. It uses genetic variants as instrumental variables (IVs) to investigate putative causal relationship between an exposure and an outcome. Traditional MR methods have mainly focussed on a two-samp...
Autores principales: | Zou, Linyi, Guo, Hui, Berzuini, Carlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720408/ https://www.ncbi.nlm.nih.gov/pubmed/33287714 http://dx.doi.org/10.1186/s12874-020-01170-0 |
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