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Mitophagy promotes sorafenib resistance through hypoxia-inducible ATAD3A dependent Axis

BACKGROUND: The identification of novel targets for recovering sorafenib resistance is pivotal for Hepatocellular carcinoma (HCC) patients. Mitophagy is the programmed degradation of mitochondria, and is likely involved in drug resistance of cancer cells. Here, we identified hyperactivated mitophagy...

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Detalles Bibliográficos
Autores principales:	Wu, Hong, Wang, Tao, Liu, Yiqiang, Li, Xin, Xu, Senlin, Wu, Changtao, Zou, Hongbo, Cao, Mianfu, Jin, Guoxiang, Lang, Jinyi, Wang, Bin, Liu, Baohua, Luo, Xiaolin, Xu, Chuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720487/ https://www.ncbi.nlm.nih.gov/pubmed/33280610 http://dx.doi.org/10.1186/s13046-020-01768-8

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