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Microglial replacement therapy: a potential therapeutic strategy for incurable CSF1R-related leukoencephalopathy

CSF1R-related leukoencephalopathy is an adult-onset leukoencephalopathy with axonal spheroids and pigmented glia caused by colony stimulating factor 1 receptor (CSF1R) gene mutations. The disease has a global distribution and currently has no cure. Individuals with CSF1R-related leukoencephalopathy...

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Detalles Bibliográficos
Autores principales: Han, Jinming, Sarlus, Heela, Wszolek, Zbigniew K., Karrenbauer, Virginija Danylaité, Harris, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720517/
https://www.ncbi.nlm.nih.gov/pubmed/33287883
http://dx.doi.org/10.1186/s40478-020-01093-3