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CD44, a marker of cancer stem cells, is positively correlated with PD-L1 expression and immune cells infiltration in lung adenocarcinoma

BACKGROUND: PD-L1 inhibitors is widely applied in lung adenocarcinoma patients. Tumor cells with high PD-L1 expression could trigger immune evasion. Cancer stem cells (CSCs) can evade from immunesurveillance due to their immunomodulating effects. However, the correlation between CSC and PD-L1 and so...

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Detalles Bibliográficos
Autores principales: Zhang, Chenyue, Wang, Hui, Wang, Xia, Zhao, Chenglong, Wang, Haiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720536/
https://www.ncbi.nlm.nih.gov/pubmed/33372595
http://dx.doi.org/10.1186/s12935-020-01671-4