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RRM2 protects against ferroptosis and is a tumor biomarker for liver cancer
BACKGROUND: Ferroptosis is the process of cell death triggered by lipid peroxides, and inhibition of glutathione (GSH) synthesis leads to ferroptosis. Liver cancer progression is closely linked to ferroptosis suppression. However, the mechanism by which inhibition of GSH synthesis suppresses potenti...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720568/ https://www.ncbi.nlm.nih.gov/pubmed/33372599 http://dx.doi.org/10.1186/s12935-020-01689-8 |