RRM2 protects against ferroptosis and is a tumor biomarker for liver cancer

BACKGROUND: Ferroptosis is the process of cell death triggered by lipid peroxides, and inhibition of glutathione (GSH) synthesis leads to ferroptosis. Liver cancer progression is closely linked to ferroptosis suppression. However, the mechanism by which inhibition of GSH synthesis suppresses potenti...

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Detalles Bibliográficos
Autores principales: Yang, Yueyue, Lin, Jiafei, Guo, Susu, Xue, Xiangfei, Wang, Yikun, Qiu, Shiyu, Cui, Jiangtao, Ma, Lifang, Zhang, Xiao, Wang, Jiayi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720568/
https://www.ncbi.nlm.nih.gov/pubmed/33372599
http://dx.doi.org/10.1186/s12935-020-01689-8

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