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Microarray analysis identifies defects in regenerative and immune response pathways in COPD airway basal cells

BACKGROUND: Airway basal cells are specialised stem cells and regenerate airway epithelium. Airway basal cells isolated from patients with COPD regenerate airway epithelium with an abnormal phenotype. We performed gene expression analysis to gain insights into the defective regenerative programme in...

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Detalles Bibliográficos
Autores principales: Pineau, Fanny, Shumyatsky, Gabriella, Owuor, Nicole, Nalamala, Nisha, Kotnala, Sudhir, Bolla, Sudhir, Marchetti, Nathaniel, Kelsen, Steven, Criner, Gerard J., Sajjan, Uma S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720690/
https://www.ncbi.nlm.nih.gov/pubmed/33313308
http://dx.doi.org/10.1183/23120541.00656-2020