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Selective amplification of hypermethylated DNA from diverse tumor types via MSRE-PCR

DNA methylation biomarkers are increasingly utilized for the detection, prognosis and monitoring of cancer. Here we use publicly-available whole genome bisulfite sequencing data to identify differentially methylated regions (cDMRs) in diverse tumor types and further define a set of genomic target re...

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Detalles Bibliográficos
Autores principales: Chapman, Karen B., Higgs, Brandon W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720775/
https://www.ncbi.nlm.nih.gov/pubmed/33315971
http://dx.doi.org/10.18632/oncotarget.27825