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Novel PI3K/Akt/mTOR signaling inhibitor, W922, prevents colorectal cancer growth via the regulation of autophagy

W922, a novel PI3K/Akt/mTOR pathway inhibitor, exhibits efficient anti-tumor effects on HCT116, MCF-7 and A549 human cancer cells compared with other synthesized compounds. The present study aimed to investigate its anti-tumor effects on colorectal cancer cells. A total, of seven different colorecta...

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Detalles Bibliográficos
Autores principales: Wang, Jin, Liang, Dong, Zhang, Xue-Pei, He, Chen-Fei, Cao, Lei, Zhang, San-Qi, Xiao, Xue, Li, Shui-Jie, Cao, Yong-Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721087/
https://www.ncbi.nlm.nih.gov/pubmed/33367926
http://dx.doi.org/10.3892/ijo.2020.5151