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Coordinated silencing of the Sp1-mediated long noncoding RNA MEG3 by EZH2 and HDAC3 as a prognostic factor in pancreatic ductal adenocarcinoma

OBJECTIVE: Pancreatic ductal adenocarcinoma (PDAC) is a disease with high mortality. Many so-called “junk” noncoding RNAs need to be discovered in PDAC. The purpose of this study was therefore to investigate the function and regulatory mechanism of the long noncoding RNA MEG3 in PDAC. METHODS: The G...

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Detalles Bibliográficos
Autores principales: Han, Ting, Zhuo, Meng, Yuan, Cuncun, Xiao, Xiuying, Cui, Jiujie, Qin, Guangrong, Wang, Liwei, Jiao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721101/
https://www.ncbi.nlm.nih.gov/pubmed/33299646
http://dx.doi.org/10.20892/j.issn.2095-3941.2019.0427