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The mutational pattern of homologous recombination (HR)-associated genes and its relevance to the immunotherapeutic response in gastric cancer

OBJECTIVE: Currently, there is an urgent need to identify immunotherapeutic biomarkers to increase the benefit of immune checkpoint inhibitors (ICIs) for patients with gastric cancer (GC). Homologous recombination deficiency (HRD) can modify the tumor immune microenvironment by increasing the presen...

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Detalles Bibliográficos
Autores principales: Fan, Yue, Ying, Haifeng, Wu, Xueying, Chen, Huan, Hu, Ying, Zhang, Henghui, Wu, Lijia, Yang, Ying, Mao, Beibei, Zheng, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721103/
https://www.ncbi.nlm.nih.gov/pubmed/33299649
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0089