Innate immune signaling in Drosophila shifts anabolic lipid metabolism from triglyceride storage to phospholipid synthesis to support immune function

During infection, cellular resources are allocated toward the metabolically-demanding processes of synthesizing and secreting effector proteins that neutralize and kill invading pathogens. In Drosophila, these effectors are antimicrobial peptides (AMPs) that are produced in the fat body, an organ th...

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Detalles Bibliográficos
Autores principales: Martínez, Brittany A., Hoyle, Rosalie G., Yeudall, Scott, Granade, Mitchell E., Harris, Thurl E., Castle, J. David, Leitinger, Norbert, Bland, Michelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721134/
https://www.ncbi.nlm.nih.gov/pubmed/33227003
http://dx.doi.org/10.1371/journal.pgen.1009192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721134/
https://www.ncbi.nlm.nih.gov/pubmed/33227003
http://dx.doi.org/10.1371/journal.pgen.1009192

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