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Innate immune signaling in Drosophila shifts anabolic lipid metabolism from triglyceride storage to phospholipid synthesis to support immune function
During infection, cellular resources are allocated toward the metabolically-demanding processes of synthesizing and secreting effector proteins that neutralize and kill invading pathogens. In Drosophila, these effectors are antimicrobial peptides (AMPs) that are produced in the fat body, an organ th...
Autores principales: | Martínez, Brittany A., Hoyle, Rosalie G., Yeudall, Scott, Granade, Mitchell E., Harris, Thurl E., Castle, J. David, Leitinger, Norbert, Bland, Michelle L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721134/ https://www.ncbi.nlm.nih.gov/pubmed/33227003 http://dx.doi.org/10.1371/journal.pgen.1009192 |
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