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Fate and propagation of endogenously formed Tau aggregates in neuronal cells

Tau accumulation in the form of neurofibrillary tangles in the brain is a hallmark of tauopathies such as Alzheimer's disease (AD). Tau aggregates accumulate in brain regions in a defined spatiotemporal pattern and may induce the aggregation of native Tau in a prion‐like manner. However, the un...

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Detalles Bibliográficos
Autores principales: Chastagner, Patricia, Loria, Frida, Vargas, Jessica Y, Tois, Josh, I Diamond, Marc, Okafo, George, Brou, Christel, Zurzolo, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721367/
https://www.ncbi.nlm.nih.gov/pubmed/33179866
http://dx.doi.org/10.15252/emmm.202012025