Cargando…

Efficient chromatin accessibility mapping in situ by nucleosome-tethered tagmentation

Chromatin accessibility mapping is a powerful approach to identify potential regulatory elements. A popular example is ATAC-seq, whereby Tn5 transposase inserts sequencing adapters into accessible DNA (‘tagmentation’). CUT&Tag is a tagmentation-based epigenomic profiling method in which antibody...

Descripción completa

Detalles Bibliográficos
Autores principales: Henikoff, Steven, Henikoff, Jorja G, Kaya-Okur, Hatice S, Ahmad, Kami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721439/
https://www.ncbi.nlm.nih.gov/pubmed/33191916
http://dx.doi.org/10.7554/eLife.63274