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Efficient chromatin accessibility mapping in situ by nucleosome-tethered tagmentation

Chromatin accessibility mapping is a powerful approach to identify potential regulatory elements. A popular example is ATAC-seq, whereby Tn5 transposase inserts sequencing adapters into accessible DNA (‘tagmentation’). CUT&Tag is a tagmentation-based epigenomic profiling method in which antibody...

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Detalles Bibliográficos
Autores principales:	Henikoff, Steven, Henikoff, Jorja G, Kaya-Okur, Hatice S, Ahmad, Kami
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721439/ https://www.ncbi.nlm.nih.gov/pubmed/33191916 http://dx.doi.org/10.7554/eLife.63274

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