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FLEXIQuant-LF to quantify protein modification extent in label-free proteomics data

Improvements in LC-MS/MS methods and technology have enabled the identification of thousands of modified peptides in a single experiment. However, protein regulation by post-translational modifications (PTMs) is not binary, making methods to quantify the modification extent crucial to understanding...

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Detalles Bibliográficos
Autores principales: Schlaffner, Christoph N, Kahnert, Konstantin, Muntel, Jan, Chauhan, Ruchi, Renard, Bernhard Y, Steen, Judith A, Steen, Hanno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721442/
https://www.ncbi.nlm.nih.gov/pubmed/33284109
http://dx.doi.org/10.7554/eLife.58783