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Exploiting the metabolic dependencies of the broad amino acid transporter SLC6A14

Tumor cells typically enhance their metabolic capacity to sustain their higher rate of growth and proliferation. One way to elevate the nutrient intake into cancer cells is to increase the expression of genes encoding amino acid transporters, which may represent targetable vulnerabilities. Here, we...

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Detalles Bibliográficos
Autores principales: Dejure, Francesca R., Butzer, Joachim, Lindemann, Ralph K., Mardin, Balca R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721610/
https://www.ncbi.nlm.nih.gov/pubmed/33400734
http://dx.doi.org/10.18632/oncotarget.27758