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Exploiting the metabolic dependencies of the broad amino acid transporter SLC6A14
Tumor cells typically enhance their metabolic capacity to sustain their higher rate of growth and proliferation. One way to elevate the nutrient intake into cancer cells is to increase the expression of genes encoding amino acid transporters, which may represent targetable vulnerabilities. Here, we...
Autores principales: | Dejure, Francesca R., Butzer, Joachim, Lindemann, Ralph K., Mardin, Balca R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721610/ https://www.ncbi.nlm.nih.gov/pubmed/33400734 http://dx.doi.org/10.18632/oncotarget.27758 |
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