Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide. For advanced HCC, there is still an unmet need for more effective therapeutic strategies. HCC is typically associated with hypoxia and the hypoxia-inducible factor (HIF) regulatory pathway plays an importa...

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Detalles Bibliográficos
Autores principales: Vanderborght, Bart, De Muynck, Kevin, Lefere, Sander, Geerts, Anja, Degroote, Helena, Verhelst, Xavier, Van Vlierberghe, Hans, Devisscher, Lindsey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721613/
https://www.ncbi.nlm.nih.gov/pubmed/33400730
http://dx.doi.org/10.18632/oncotarget.27830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721613/
https://www.ncbi.nlm.nih.gov/pubmed/33400730
http://dx.doi.org/10.18632/oncotarget.27830

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