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Novel allosteric inhibition of phosphoribulokinase identified by ensemble kinetic modeling of Synechocystis sp. PCC 6803 metabolism

The present study attempted a computer simulation of the metabolism of a model cyanobacteria, Synechocystis sp. PCC 6803 (PCC 6803) to predict allosteric inhibitions that are likely to occur in photoautotrophic and mixotrophic conditions as well as in a metabolically engineered strain. PCC 6803 is a...

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Detalles Bibliográficos
Autores principales: Nishiguchi, Hiroki, Liao, James, Shimizu, Hiroshi, Matsuda, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721636/
https://www.ncbi.nlm.nih.gov/pubmed/33312875
http://dx.doi.org/10.1016/j.mec.2020.e00153