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Population-Matched Transcriptome Prediction Increases TWAS Discovery and Replication Rate
Most genome-wide association studies (GWAS) and transcriptome-wide association studies (TWAS) focus on European populations; however, these results cannot always be accurately applied to non-European populations due to genetic architecture differences. Using GWAS summary statistics in the Population...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721644/ https://www.ncbi.nlm.nih.gov/pubmed/33313492 http://dx.doi.org/10.1016/j.isci.2020.101850 |