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The Human RNA Helicase DDX21 Presents a Dimerization Interface Necessary for Helicase Activity

Members of the DEAD-box helicase family are involved in all fundamental processes of RNA metabolism, and as such, their malfunction is associated with various diseases. Currently, whether and how oligomerization impacts their biochemical and biological functions is not well understood. In this work,...

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Detalles Bibliográficos
Autores principales: Marcaida, Maria J., Kauzlaric, Annamaria, Duperrex, Alice, Sülzle, Jenny, Moncrieffe, Martin C., Adebajo, Damilola, Manley, Suliana, Trono, Didier, Dal Peraro, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721647/
https://www.ncbi.nlm.nih.gov/pubmed/33313488
http://dx.doi.org/10.1016/j.isci.2020.101811