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The Human RNA Helicase DDX21 Presents a Dimerization Interface Necessary for Helicase Activity
Members of the DEAD-box helicase family are involved in all fundamental processes of RNA metabolism, and as such, their malfunction is associated with various diseases. Currently, whether and how oligomerization impacts their biochemical and biological functions is not well understood. In this work,...
Autores principales: | Marcaida, Maria J., Kauzlaric, Annamaria, Duperrex, Alice, Sülzle, Jenny, Moncrieffe, Martin C., Adebajo, Damilola, Manley, Suliana, Trono, Didier, Dal Peraro, Matteo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721647/ https://www.ncbi.nlm.nih.gov/pubmed/33313488 http://dx.doi.org/10.1016/j.isci.2020.101811 |
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