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The G protein coupled receptor CXCR4 designed by the QTY code becomes more hydrophilic and retains cell signaling activity

G protein-coupled receptors (GPCRs) are vital for diverse biological functions, including vision, smell, and aging. They are involved in a wide range of diseases, and are among the most important targets of medicinal drugs. Tools that facilitate GPCR studies or GPCR-based technologies or therapies a...

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Detalles Bibliográficos
Autores principales: Tegler, Lotta, Corin, Karolina, Pick, Horst, Brookes, Jennifer, Skuhersky, Michael, Vogel, Horst, Zhang, Shuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721705/
https://www.ncbi.nlm.nih.gov/pubmed/33288780
http://dx.doi.org/10.1038/s41598-020-77659-x