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Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors

Therapy resistance is a major roadblock in oncology. Exacerbation of molecular dysfunctions typical of cancer cells have proven effective in twisting oncogenic mechanisms to lethal conditions, thus offering new therapeutic avenues for cancer treatment. Here, we demonstrate that selective agonists of...

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Detalles Bibliográficos
Autores principales: Alaimo, Alessandro, Lorenzoni, Marco, Ambrosino, Paolo, Bertossi, Arianna, Bisio, Alessandra, Macchia, Alice, Zoni, Eugenio, Genovesi, Sacha, Cambuli, Francesco, Foletto, Veronica, De Felice, Dario, Soldovieri, Maria Virginia, Mosca, Ilaria, Gandolfi, Francesco, Brunelli, Matteo, Petris, Gianluca, Cereseto, Anna, Villarroel, Alvaro, Thalmann, George, Carbone, Francesco Giuseppe, Kruithof-de Julio, Marianna, Barbareschi, Mattia, Romanel, Alessandro, Taglialatela, Maurizio, Lunardi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721710/
https://www.ncbi.nlm.nih.gov/pubmed/33288740
http://dx.doi.org/10.1038/s41419-020-03256-5