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Detailed evaluation of the upper airway in the Dp(16)1Yey mouse model of Down syndrome

A high prevalence of obstructive sleep apnea (OSA) has been reported in Down syndrome (DS) owing to the coexistence of multiple predisposing factors related to its genetic abnormality, posing a challenge for the management of OSA. We hypothesized that DS mice recapitulate craniofacial abnormalities...

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Detalles Bibliográficos
Autores principales: Takahashi, Tatsunori, Sakai, Noriaki, Iwasaki, Tomonori, Doyle, Timothy C., Mobley, William C., Nishino, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721723/
https://www.ncbi.nlm.nih.gov/pubmed/33288820
http://dx.doi.org/10.1038/s41598-020-78278-2